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This is one of the "smartest" models you can fit on a 24GB GPU now, with no offloading and very little quantization loss. It feels big and insightful, like a better (albeit dry) Llama 3.3 70B with thinking, and with more STEM world knowledge than QwQ 32B, but comfortably fits thanks the new exl3 quantization!
You need to use a backend that support exl3, like (at the moment) text-gen-web-ui or (soon) TabbyAPI.
There's a "What's missing" section there that lists ROCm, so I'm pretty sure it's planned to be added
That, and exl2 has ROCm support.
There was always the bugaboo of uttering a prayer to get rocm flash attention working (come on, AMD...), but exl3 has plans to switch to flashinfer, which should eliminate that issue.