this post was submitted on 01 Jun 2025
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haha, I don't know doctor mike.
There is a whole spectrum of glucose control.
At the one end we have
Throw in intermittent fasting of some type, and you have a bit more variability. The literature I've seen indicates most of the major benefits are seen proportionally to the time glucose isn't elevated.
Broccoli at 7g of carbs per 100g serving could fit into most of the keto protocols, its more of a carb budget then a restriction of all carbs.
The blood/brain barrier can become insulin resistant and when that happens the ratio of glucose and insulin in the brain itself isn't the same as in the blood stream, so even though there are major glucose levels in the brain it can't be utilized without insulin in the right ratio. Interestingly ketones pass through the blood brain barrier with no resistance, and can be utilized for energy for most brain function 70-95% depending on the keto adaption period... There are some non-human studies on how ketones can signal repair pathways in mice brains to dispose of misfolded proteins, though its a bit of a black box at the moment.
I bring up the mechanisms we know about the brain to indicate that some neurological conditions may benefit more from ketones persistently then just low carb, but i do agree intermittent fasting is a great place to start.
If the condition is serious patients can use a ketone and glucose monitor to track their carbohydrate tolerance and avoid events. I.E. everyone's carbohydrate tolerance is different based on genetics, muscle uptake, GI function, etc. The indexes above are conservative.