I liked the twist of anger being the virus, but felt like the satire was pretty muted compared to what they could have done with the concept.

The sharpest jab, I think, was subtle. That was when Hermes narrated the typical scifi/magic mumbo-jumbo that comprised the solution (like, reverse the polarity of the dark matter tachyon field in the SIF and feed it into the spacetime rift through the deflector array), but in this case it was an accurate description of a real vaccine. Dressing up the vaccine with the language of shady miracle cures might have worked in the real world, if it weren't for those pesky medical ethics.

That was a nice twist and I sort of enjoyed the omicronians "omicron" mutation.

Yes, the episode is good. Still the topic feels dated and beaten to death.

There are infinite ways to change the specific virus for a parody. That doesn't really change that it's parodying a situation that was already parodied to death by 2022.

I think it's mostly well written, and there are some good subtle and non-subtle jokes, but it came way too late.