This is what I've taken to lately... If they're a religious conservative.

If they come from a less unhinged, though still clearly misguided, point or view, I play nicer.

I grew up in a conservative family, though, and went to a religious school. Which why I'm a Marxist atheist now. Which is also why I have no tolerance for religious conservatives and dunk on them relentlessly with their own Bible.

EDIT: I should add that I'm nicer to neighborhood liberals because I think they more often come from a standpoint of wanting what seems to be better for everyone than what we have now. Conservatives just want subjugation, so fuck them.