I love Space Base. The designer is a mad genius. But I will say it’s more fun with more people and it has a lot of setup. Mystic Vale is another by him that works well for two and is slightly less piecey. There’s an app if you want to try it for cheap.

But if you want extremely easy to learn, not too hard to set up, and quite fun to play, Santorini is phenomenal. It’s literally about as easy to learn as checkers. The instructions are basically one page for the core game and then you can spice it up by adding special powers. But the core mechanic is so elegantly simple it’s hard to believe how little there Is to learn.

+1, a majority of my play has been 2P. But I agree it's better with more. Pretty easy to learn too.