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ArcGis Pro in Wine?
(feddit.de)
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Unless things have changed, graphics card passthrough is tough to use because you need two graphics cards. The one sent to the VM can't be used on the host if you plan on using the guest. For laptops this can be impossible to reconcile, and even for desktops this can be... weird.
Actually, things have changed - you can passthru with just a single GPU now, and for many users, it's actually more stable/reliable than a dual-GPU setup (as you do mention, it can be "weird"). There is a catch however, and that is of course you can't use/switch to your host OS while the guest is running, but that shouldn't be an issue anyways if you're going to be working out of the guest OS. There are scripts available that make this switchover automatic and seamless.
https://github.com/QaidVoid/Complete-Single-GPU-Passthrough
Here's a handy video that illustrated what this looks like: https://www.youtube.com/watch?v=eTWf5D092VY
Here is an alternative Piped link(s):
https://www.piped.video/watch?v=eTWf5D092VY
Piped is a privacy-respecting open-source alternative frontend to YouTube.
I'm open-source; check me out at GitHub.