So again and again and again, I was not arguing against the abandonware issue. I take issue with how the problem is being stop-gapped in this current situation and not in some hypothetical alternate timeline.

Instruments like the ones we use are super expensive

Great. I didn't imply otherwise.

On top of that most people here barely understand computer and software

So the lab guy maintaining Windows 95 era computer's hardware, barely understands computers. Got it. I suppose this same lab guy won't be able to do anything even if the source code was available and would still being doing the same job.

What you’re suggesting is treating the symptoms but not the disease. Making certain file formats compatible with other programs is not an easy undertaking and certainly not for people without IT experience.

I didn't say it isn't. I said they've had ~20 years to figure it out. What would source code being available solve for them then? We could assume other people would come together to maintain it, sure. I've also talked about other solutions in replies. There are even more solutions. I wasn't trying to cover all bases there. It is just that within a couple of decades this has been a problem, there has been plenty of time to solve it.

Software for tools this expensive should either be open source from the get-go or immediately open-sourced as soon as it’s abandoned or company goes bust

Oh OK, so that makes it less complicated. I thought the assumption here is that, in general, anyone in that lab barely understands a computer or how software works. So, who's going to maintain it? Hopefully, others, sure. I actually do talk about this in other replies and how it is something I support and that, in this case, the solution is to deliver the source with the product. FOSS is fantastic. Why can't that just be done now by these same interested parties? Or are we back to "can't computer" again? Then what good is the source code anyway?

But again, that's a "what-if things were different" which isn't what I was discussing. I was discussing this specific, real and fairly common issue of attempting to maintain EOL/EOSL hardware. It is a losing game and eventually, it just isn't going to work anymore.

Even with plenty of funding to workaround the issue that shouldn’t be necessary, it’s a waste of time and money just so a greedy company can make a few extra bucks.

Alright, the source code is available for this person. Let's just say that. What now?

What can be done right now, is fairly straight forward and there are numerous step-by-step guides. That's to virtualize the environment. There is also an option to use hardware passthru, if there is some unmentioned piece of equipment. This could be done with some old laptop or computer that you've probably tossed in the dumpster 10 years ago. The cost is likely just some labor. Perhaps that same lab guy can poke around or if they're at a university, have their department reach out to the Computer Science or other IT related teaching department and ask if there are any volunteers, even for undergrads. There are very likely students that would want to take it on, just because they want to figure it out and nothing else.

There may be an edge case where it won't work due to some embedded proprietary hardware but that's yet another hypothetical issue at stake which is to open source hardware. That's great. Who's going to make that work in a modern motherboard? The person that you've supposed can't do that because they barely understand a computer at all?

In this current reality, with the specific part of the post I am addressing, the solution currently of sustaining something ancient with diminishing supply is definitely not the answer. That is the point I was making. There is a potential of ~20 years of labor hours. There is a potential of ~20 years of portioning of budgets. And let's not forget, according to them, it is "CRITICAL" to their operations. Yet, it is maintained by a "lab guy" who may or may not have anything other than a basic understanding of computers using hardware that's no longer made and hoping to cannibalize, use second hand and find in bins somewhere.

If this "lab guy" isn't up to the task, then why are they entrusted with something so critical with nothing done about it in approximately two decades? If they are up to the task, then why isn't a solution with longevity and real risk mitigation being taken on? It is a short-sighted mentality to just kick it down the road over and over again plainly hoping something critical is never lost.