Well, the good news is that cancer and appendicitis would be considered diseases which the spell explicitly cures when making the body "whole" for the resurrection.

The bad news is that the Weave does not differentiate between things removed purposefully and things lost in combat. So it is 100% untransing your gender.

But some more good news is that if a mage concentrates on True Polymorph for its full 1-hour duration the effects become permanent unless dispelled. So they can trans your gender so effectively they can actually give you all the fully functional bits and bobs.

In my homebrew setting I have a major band of retired adventurers made up of scrapped character concepts from over the years. One of them actually travels the land among other things transing the genders of people born into the wrong body as they were.