If you haven't heard of it, this island has a population that the world has collectively decided to leave alone, mostly because they have proven, on multiple occasions, that they absolutely do not want visitors. Like, arrow-to-death anyone attempting to land or even visit near their shores.

This probably cannot go on forever... but maybe, it could. Essentially, we are already implementing a 'Prime Directive' of sorts here. Would the 23rd, 24th, ... centuries in Star Trek canon still have this little island on Earth, isolated from not just from Earth's own unified Federation society, but from the greater Federation races? What steps would the Federation and Earth take to maintain their isolation and the ecosystem on which they depend?

Would make for an interesting episode, or at least a cool side-note reference in one :)