No. Do you have any idea how fucking difficult and complex rotations and angle math is when it becomes 3d? Quaternions, rotational matrices, imaginary numbers, gimbal lock. Things get really complicated really quick. Not every rotation related problem can even be explained and solved by modern mathematics as it is. How do you handle rotational velocity relative to a parent object so you can make a flight simulator? You can't. The "solution" to this problem is to find a different or non mathematic way to accomplish approximately the same thing.

Making things 4d would be even more ridiculous. I'd even go as far as to speculate they'll never fully figure out all the details around how to simulate 4d.