Adobe After Effects. Despite being an unstable spaghetti code nightmare, there is no other viable option for professional motion graphics designers.
Free and Open Source Software
If it's free and open source and it's also software, it can be discussed here. Subcommunity of Technology.
This community's icon was made by Aaron Schneider, under the CC-BY-NC-SA 4.0 license.
I want to jump to linux, but the prospect of starting from scratch on a new OS (or even a reinstall of windows) is just not feasible right now.
Sublime text. It is just so fucking good! Much more performant than even nvim.
Onenote! I use it for school and work, and love the syncing capability and the flexibility in structuring and organizing my notes. I also like the keyboard shortcuts and the way it can dock to a side of the screen to keep the main content visible
Would https://anytype.io/ be a replacement? It's very new so you might not have heard of it. It's designed like Notion, but it might have everything you need.
If your needs are more simple, https://notesnook.com/ could be worth looking into.
Other FOSS options are Joplin and Logseq. I'm an Obsidian user myself; not FOSS but the storage format is completely open which is the most important to me.
I adore obsidian, but would love to see an open source software that is on the same level. The extensibility and keyboard-shortcut driven nature of Obsidian makes it a dream to use!
firmware/drivers
Ableton Live, Presonus Studio One and about a million VST plugins. Digital audio workstations and software instruments/effects are an area where open-source has made only limited inroads. Ardour was decent last time I used it, but since I got into Ableton Live with Push it's hard to go back to other things.
It's not FOSS or free, but Reaper at least has a native Linux version, and it's a great DAW.
Nationwide banking.
For home and work, none, locally. The problem now is Google and MS Teams, LinkedIn, Github, etc. That's the new battle ground. They would make us thin clients to their mainframe and that we must rent access.
Intuit software, specifically TurboTax. This also may become obsolete to replace if the IRS will give out free software as rumored for next year, but I'm surprised nothing as intuitive ^pun ^heh or user-friendly has popped up. Maybe I need to do more research, not sure.
Pretty much anything on my phone. Though I have recently found f-droid, and through that I found Phonograph. I wish open street maps could replace google maps, but I really don't know what it's trying to do.
Depends on your country, but where I live Open Streetmap is better than Google's map. I hear OsmAnd is a great app, but I don't use a smartphone so I haven't tested it. I just know that their very compact offline maps are impressive.
I prefer Organic Maps as an OSM Android App, I've found it to be a bit easier to use and more reliable than OsmAnd!