I have the dymo label maker 160, it doesn't have any DRM that I'm aware of (at least I used generic labels with no issue and it's easy to find compatible refills) and I like that it has a qwerty layout, since some annoyingly have an ABC layout which is a pain to use.
My only gripe is that it doesn't have a ton of symbols though it has a decent selection, and even though the text can go small enough for like 3 lines it only lets you do 2 lines on top of each other. Also all non alphanumeric (apostrophes, parentheses, etc) are in the symbol menu instead of having dedicated keys but that's not terrible.
It's also only ~$30 which is really reasonable, I've gotten a ton of use out of mine.