I don't think so but with external scripts you can always get chatgpt to write you some greasemonky scripts to do it
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Just remembered Ublock Origin filters also work nice with fediverse sites, although I would prefer to completely purge posts with links I avoid.
But for those curious, here's an example filter I just cooked:
lemm.ee##a[class="fst-italic link-dark link-opacity-75 link-opacity-100-hover"]:has-text(here_goes_the_domain_as_displayed_under_the_post_title):upward(div[class="post-listing mt-2"])
So as an hypothetical example, if for some reason I have a problem with the sh.itjust.works
instance, I could make this:
lemm.ee##a[class="fst-italic link-dark link-opacity-75 link-opacity-100-hover"]:has-text(sh.itjust.works):upward(div[class="post-listing mt-2"])
And it ends up looking like this:
https://imgur.com/a/GuOspst
Filter active on the left, and not active on the right.
Shit, the fucking simple solution. classic
Similar question here: https://lemmy.world/post/19194148
In summary: some interfaces and clients allow for that, but not the Lemmy default
Post link in case anyone reading this from lemm.ee so there are no need to leave the instance to read the hyperlinked post: https://lemm.ee/post/40968078