50,000 people used to live 'ere, ...

ASSUMING CONTROL

DIRECT INTERVENTION IS NECESSARY

"If you can't stand the heat, go put your tiny balls in the freezer!"

-Catalina, GTA San Andreas

Also a big fan of C-C-C-COMBO BREAKER!

• "Alley-oop!"
• "You can't have a rainbow without Reyn, baby!"
• "Give it some Oomph!"
• "Now it's Reyn time!"
• "Man, wha' a buncha jokas!"

Yeah, I played too much Xenoblade. Honorable mentions to:

• "Hear that Noah? Lanz wants something a bit meatier"

The carrier has arrived.

Were it so easy.

YoU cAnT jUsT sHoOt A hOlE tHrOuGh MaRs!

Oh I know what the ladies like.

"Had to be me. Someone else might have gotten it wrong"

I will pay you to kill yourself

Boy!

My life for Aiur

Don toridos? Misspelled wrong

Live for the swarm

"Stay a while, and listen."

"With my brains and your brawn, we'll make an excellent team!"

"Stop rocking the boat, you're making me sea sick!"

"7 minutes, 7 minutes is all the time I can spare to play with you"

"... There's a pimento taco, a pimentaco in the glovebox"

"Ride ze shoopuf?"

"The numbers mason, what do they mean?"

"Have some faith"

"Tank beats everything"

"I want to get off Mr Bones Wild Ride." (Rollercoaster Tycoon - PC)

"Stay awhile... Stay FOREVER!!!" (Impossible Mission - C64)

Time is money friend.

My name is Guybrush Threpwood. I'm a mighty pirate.

Sir, permission to leave the station?
For what purpose Master Chief?
To give the Covenant back their bomb...

Haven't seen this one mentioned yet.

Oh, I know what the ladies like.

Edit: From a different game.

"He's fucked in the head, the world's fucked in the head, and YOU'RE fucked in the head because MY fucked up head is inside it. Guess if you wanna save the world, that's the first step; get fucked in the head."

"Hello my friend. Stay a while and listen."

"PUT DISPENSER HERE"

"Would you kindly?"

"Patrolling Mojave almost makes you wish for nuclear winter"

"ALL YOU HAD TO DO WAS FOLLOW THE DAMN TRAIN CJ"

"Rise and shine mr. Freeman, rise and shine"

"Hey, you finally awake"

EDIT:

"I make my own luck"

(Several monologue from ezio saga and kenway saga is worthwhile unfortunately I couldn't fully text it all :( )

"Guys the drill, go get it"

"Ahhh, I need my medic bag"

"Mission failed, we will get them next time"

"ENEMY AC130 ABOVE!"

"Engravings gives you no tactical advantage whatsoever"

"Boss, try to remember the basic CQC"

"The numbers mason, what do they mean" ~~perfect response when someone suddenly pop in 6 digits nuclear code~~

"Victory can't be achieved without sacrifice"

"The flags may be different, but the methods are the same"

War... War never changes

Titanfall|2

Upon your Titan noticing a new weapon that's more powerful, the main character comments "I think someone's in love..."

BT's response is priceless.

BT-7274: "The human concept of love requires admiration, attraction, devotion, and respect. Conclusion: I am 50% in love."

wololooooo

"Had to be me."

Also, there was a Warhammer RTS that had "AHH my spleen!!!" Which I never got over.

"The enemy has captured a command post"

"deeeeeeeaaaaaath" -Black and White

And then every once in a while if your name was common enough it would whisper your name instead. Freaked me out first time it happened.

FISSION MAILED

And

I hear it's amazing when the famous purple stuffed worm in flap-jaw space with the tuning fork does a raw blink on Hara-Kiri Rock. I need scissors! 61!

A man chooses, a slave obeys.

"Beep beep beep" - sputnik

Voiced by Lenard Nemoy in Civ 4

• I am Error.
• All your base are belong to us.
• It's dangerous to go alone. Take this! Why yes I did grow up in the 80s & 90s.

Bonus from a newer game: "What have I told you? People are a renewable resource!"

"They were all dead ..."

First words of Max Payne. But I always forget what comes next. Something about final gunshot something

"I am legally obliged to tell you, that I am not a real docter" Dr. Zed from Borderlands (2)

You have no chance to survive, make your time.

Still sane, Exile?

"You must gather your party before venturing forth." - Baldur's Gate 2