Sisko was killed in TNG's universe. Sisko survived in DS9's universe due to the prophets saving him. The Trek universe diverged at Wolf 359.
The Dominion War has drastically different outcomes. Existential crisis in one universe where Sisko does a lot of meddling; barely mentioned in the other.
The biggest change to the cast is that Worf marries Jadzia Dax and becomes Ambassador to the Klingon Empire in one universe; in the other universe, he does a brief inconsequential stint at DS9 (without Sisko), never marries, then returns to the Enterprise E as pretty much the same character from TNG, and at some later point, he gets the Enterprise E destroyed.
The Picard timeline is set in the universe where Sisko died at Wolf 359.
This was the first movie I ever took my kids to see at the cinema (out of two movies ever). I thought it was good but the re-watch-ability is low. It's not a genre thing, it's just that Disney hasn't really put out anything good since Moana. Frozen 2 is a terrible movie. The one in Colombia was a terrible movie. Raya was insulting.
There's a reason that Iger was brought back.
Also, mentioned many times, Disney doesn't get to define or legitimize solarpunk any more than they get to define Southeast Asian culture with their generic "age of empires" music score.