Most of the people I'm talking about were either born there or have lived there for longer than Ukraine has existed as a state. Those people should be the ones in charge of the fate of Crimea, regardless of their ethnicity. I don't believe in blood and soil nationalism where only certain ethnicities get to be full citizens.

By "the Uighers" I assume you're talking about Xinjiang? The most serious separatist movement there is the Eastern Turkistan Islamic Movement, the US recognized these guys as a terrorist group in 2002. The US continued to recognize them as a terrorist group until 2020, when the US decided that it would be more politically convenient for them to not be terrorists anymore. The overall populace supports the central government. It's 90+% approval for China overall, I can't find a breakdown by region. If the people of Xinjiang were to lose faith in the central government and decided to go their own way then I would support them. The important part is that is has to be the people, not terror groups, not US-backed NGOs, and not US-backed protest movements, that support the separatism movement.