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Babies in Nigeria are being born with antibiotic resistant bacteria, researchers find
(theconversation.com)
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Phages are pretty cool, but bacteria do develop phage resistance as well. Phages also can evolve to evade those resistances, in a co-evolutionary battle, but also Phages can still be seen as antigens to our own body.
A recent case-study: https://www.upmc.com/media/news/021424-phage-therapy
To avoid reading the whole article: Antibiotics no-longer worked for a patient in 2020 that developed an infection after needing immunosuppression for treatment of an autoimmune condition, so they tried phage therapy.
quote from the phage treatment section:
I'm not disagreeing with the benefits of Phage Therapy, just that it isn't likely a magic solution all on it's own, and can still suffer similar resistance issues as antibiotics have. I'm a fan of multipronged attack vectors, to reduce the chance of developing progressive resistances (ie. wipe out the whole colony), and the more tools we have for that, the better.
That just goes to show how complex the immune system is. Even though we learn more about it all the time, I get the feeling that we’re only scratching the surface.
In part, yes. Mostly it goes to show that bacteria are highly adaptable, and highly dangerous. Between the quick generation rate, and their ability to pick up genes as adult individuals, they can evolve faster than we can test new treatments against them. It's only thanks to a complex immune system, that we get to live at all.