Don't. The last thing we want is to associate the fediverse with some kind of anarchist world where everything is trash and everyone insults everyone. Leave the memers to reddit.
Reddit Migration
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They don't need the traffic, just use the fediverse instead.
The best de- endorsement will come from people's experience on reddit as the quality of user engagement drops. There are people who genuinely will never give a shit and will stay there, but those are exactly the sort of lazy minds who made up the critical mass of the shallow "hivemind." Id rather we make this a community that encourages independent thought more than bandwagoning.
Don't waste your time engaging them on that platform unless you're a child, douchebag, or troll. If your posts are actually good content, it sends a mixed message that good independent thinking redditors are whethering the shitstorm. Your actions will speak louder than your words, and our collective absence from their platform will speak volumes.
If you're planning on continuing protesting there, then yes. Only dedicate any posts and comments to the protest and for protest purposes. Otherwise, the best thing to do is delete and move on. Like other comments said, it's all just traffic for them, however if you're going to be there anyway, you may as well be there for a cause.