You need to post your model #, or at least year and chipsets. ASUS releases refreshes every uear. Your current kernel version would be helpful as well.

I have a newer Zenbook and can confirm when I first got it, and wiped windows to put Ubuntu on it, audio didn't work from the speakers. Headphones worked just fine. There's a blog from some Asus dev community documenting the issues and resolution. I'm on mobile right now and can't find it. I can confirm it was addressed on Fedora a few kernel releases back though and that all is well. I'll post the blog link shortly. Per post above please provide your model number.

Edit: typos

2023 14-inch oled i5 here. there was an easy fix for no audio on speakers, a udev drop-in iirc. it's been an awesome machine all round. on mobile now but i might post a link later.

I have a Zenbook 13 (model UX331F), bought new right around the start of COVID. Installed Linux Mint maybe 6 months ago, audio works just fine, and I didn't have to do anything special, it just worked right out of the box. I had tried Pop_OS before Mint and I don't remember any audio issues there either.

I use a Zenbook 14 (an old one though from 2017) and I've not had audio issues on fedora since I made the switch to Linux last year. One thing I do still have issues with is sometimes it fails to sleep/suspend correctly. This isn't a consistent issue though and it seems to be a gamble on if each update will fix it or make it worse. Still not been a big enough issue to make me stop using Linux.

But yeah to answer your question, I've had no audio issues on my Zenbook 14 (other than a slight popping type noise when audio starts playing when I use headphones)