Another bit of gold from ICFP 2023 by Pjotr Prins of the University of Tennessee.

The actual title of the talk is "Why code in Python+C if you can code in Lisp+Zig?" but the "Lisp" in this case is actually Guile Scheme. I didn't know this, but Zig uses the C ABI so it binds to any language that can do FFI bindings to C, including most Scheme and Common Lisp implementations. But why don't I just post the abstract here:

"Most bioinformatics software today is written in Python and for performance C is used. Lisp has been around for over half a century and here I don’t have to tell how or why programming Lisp is great. I will talk about Zig as a minimalistic new language that is unapologetically focused on performance, tellingly with a blazingly fast compiler. It is advertised as a replacement for Thompson, Ritchie, and Kernighan’s C, but it may even replace C++ in places. Zig uses the C-ABI and does not do garbage collection, so it is ideal for binding against other languages. In this talk I will present combining GNU Guile Lisp with Zig. I’ll argue that everyone needs two languages: one for quick coding and one for performance. With Guile and Zig you get both at the same time and you won’t have to fight the Rust borrow checker either."