yeah, unfortunately the CoC rules have always been kind of a mess. it still has a lot of that early RPG "stream of consciousness" aspect to it.
But yeah, at the end of the day, the number of rules you have is far more relevant to how many "exploits" there are, so CoC/VtM being less "crunchy" will result in less exploits.
I mean, as i stated, i can't really vouch or argue against pf2e, since i dont play it and haven't really read the rules of it since it was in playtest. That said, just googling, i see some things that could be considered exploits like a reddit thread talking about being able to do 520 damage in one attack, some chatter about a "resentment witch" being able to make power word stun or color spray effectively permanent, and a youtube video by the rules lawyer about "OP builds", so it seems like there's at least some system exploitation going on.
Obviously a tighter controlled system is less vulnerable to exploitation (see D&D 4e), but that also doesn't mean that is necessarily doesn't exist. Another counter example system with lots of rules and lots of exploitation of them would be shadowrun, especially older versions, which were even worse than D&D in some respects.