Unless you're writing ruby on rails on a 13" macbook, you'll run into Gnome's limitations when working.
Gnome is in many ways so focused that it makes a lot of productivity use impossible. You always have to open the menu to launch software, you've got no system tray, and worst of all, Gnome apps are so simplified that you constantly run into the limitations when using it productively.
When working with dozens of windows open at the same time across multiple monitors, I'm a fan of KDE. And KDE apps tend to also have all the extra features I need to handle weird situations, files, and edge cases.
I tried that, but IMO it's much simpler and more robust to just configure KDE than to install a dozen Gnome extensions that end up broken after updates anyway.