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Charming

Hunkular

Unflappable

Dilf

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submitted 1 hour ago by Zerush@lemmy.ml to c/science@lemmy.ml

New research reveals that the DNA switches controlling human finger development originated from genes that regulated fish cloacas 380 million years ago[^1].

"Rather than building a new regulatory system for the digits, nature has repurposed an existing mechanism, initially active in the cloaca," explains developmental geneticist Denis Duboule from the University of Geneva[^1].

The research team discovered this by comparing fish and mouse genomes, focusing on Hoxd genes. When they tagged DNA switches with fluorescent markers, these lit up in mouse digits but in fish cloacas. Deleting these genetic elements using CRISPR-Cas9 disrupted finger development in mice and cloaca formation in fish[^1].

"The common feature between the cloaca and the digits is that they represent terminal parts," notes geneticist Aurélie Hintermann. "Sometimes they are the end of tubes in the digestive system, sometimes the end of feet and hands"[^1].

[^1]: ScienceAlert - Fish Buttholes May Be The Reason We Now Have Fingers, Study Finds

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submitted 12 minutes ago by bot@lemmit.online to c/fosscad@lemmit.online
This is an automated archive made by the Lemmit Bot.

The original was posted on /r/fosscad by /u/Senor_TJ on 2025-09-22 03:07:54+00:00.

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submitted 12 minutes ago* (last edited 12 minutes ago) by solo@slrpnk.net to c/biodiversity@mander.xyz
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submitted 2 hours ago by Blaze@piefed.zip to c/privacy@programming.dev
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submitted 1 hour ago by simple@piefed.social to c/games@lemmy.world

Game Information

Game Title: Silent Hill f

Platforms:

  • PC (Sep 24, 2025)
  • Xbox Series X/S (Sep 24, 2025)
  • PlayStation 5 (Sep 24, 2025)

Trailers:

Publisher: KONAMI

Review Aggregator:

OpenCritic - 85 average - 80% recommended - 46 reviews

Critic Reviews

ACG - Jeremy Penter - Buy

"Silent Hill F's changes to the atmosphere, location, and general feel makes it one of my favorite Silent Hill games. However, long time fans may chaff at the adjustments."


Atarita - Furkan Oğur - Turkish - 75 / 100

Silent Hill F is the first new entry in the series in a long time. While it gets some things right, it falls short in others. Even though it doesn’t fully capture the classic Silent Hill feel, it’s still a good game.


CGMagazine - Brendan Frye - 9 / 10

NeoBards Entertainment has taken bold risks with Silent Hill f, and the result is one of the most unsettling, personal and rewarding horror games in years.


COGconnected - Jaz Sagoo - 90 / 100

Quote not yet available


Dexerto - James Busby - 5 / 5

Silent Hill f is a bold new direction for Konami’s iconic survival horror series. While it may put a heavier emphasis on combat, NeoBards has expertly concocted a nightmarish cocktail oozing with enough stomach-churning monsters, disgustingly beautiful environments, and psychological dread to be just as good, if not better than, Silent Hill 2.

Hinako’s world is suffocating and compelling, and I can’t wait to delve even further into the dark, damp town of Ebisugaoka to uncover more endings. If this is the quality we can expect from Silent Hill going forward, then I have never been more excited to step into its fog-filled future.


Endless Mode - Elijah Gonzalez - 90 / 100

It’s a sequel that understands what makes these games tick, both in the moment-to-moment particulars of being trapped in a fog bank where you can’t see five feet in front of you, and in the deeper specifics of using scares to navigate the fraying psyche of its protagonist.


Enternity.gr - Konstantinos Kalkanis - Greek - 7 / 10

Silent Hill f, although flawed, shows great promise for Konami's future plans for Silent Hill.


Game8 - Allisandra Reyes - 96 / 100

Silent Hill f is a bold step forward for the franchise, blending its trademark psychological horror with inventive gameplay systems that push survival horror into new territory. The story grips you, the visuals unsettle you, and the music seeps into your bones. While forced combat encounters and a few glitches keep it from perfection, its depth, multiple endings, and replay value make it an unforgettable experience.


GameSpot - Jessica Cogswell - 9 / 10

With its brilliant writing, haunting atmosphere, well-designed gameplay, and spectacular visuals, Silent Hill f sets a new benchmark for the Silent Hill series.


Gamepressure - Sebastian Kasparek - 9.5 / 10

After many long years, Silent Hill has received its most exceptional installment, reintroducing the series to the Premier League of horror and regaining its reputation as the pinnacle of virtual terror.


Gamer Guides - Ben Chard - 92 / 100

Silent Hill f lives up to the series’ legacy of offering a fantastic story that gets you thinking about more than what you see. A fun combat system, beautiful visuals, and a fantastic soundtrack only add to what is one of the best games of the year.


IGN India - Rayan Sayyed - 9 / 10

Silent Hill f pushes the series in a bold new direction without losing its soul. The Japanese setting gives the game a fresh identity while still feeling unmistakably like Silent Hill. With a story rich in character and classic gameplay that feels familiar yet refreshed, this is the revival the series has been waiting for, and it sets the stage for Silent Hill to grow in a distinct direction.


IGN Italy - Alessandro Digioia - Italian - 7.5 / 10

Silent Hill f is a compelling yet flawed return for Konami's iconic horror series: narratively strong and visually striking, it immerses players in a haunting psychological nightmare set in the eerie Japanese town of Ebisugaoka. Hinako's touching and unsettling story is the highlight, but the experience is held back by basic combat, limited enemy types, and a design that requires multiple playthroughs to fully understand the plot without enough gameplay variety. Despite interesting ideas and solid presentation, the game loses momentum over time, feeling repetitive and lessening its emotional impact.


IGN Spain - Mario Sánchez - Spanish - 10 / 10

Silent Hill f takes us to 1960s Japan with a dark, symbolic, and psychologically deep story. It combines exploration, clever puzzles, and more complex combat than previous entries, while still retaining the essence of the series.


Loot Level Chill - Chris White - 9 / 10

Silent Hill f is genuinely unnerving, with a strong story and intense combat that earns its place as a worthy entry in the series.


MonsterVine - James Carr - 3.5 / 5

Silent Hill f delivers a compelling and creepy horror experience, with unique enemies and environments that feel smartly focused on telling Hinako's story. The focus on societal expectations of women and the competition forced upon them, even between friends and sisters, gives the horror elements a more pointed focus. It delivers on themes throughout, and while the combat is only just fine, some of the more compelling ideas, like the economy of Silent Hill f create a compelling and spooky experience. Obtuse puzzles and a lack of variety in combat hold Silent Hill f back from reaching the peak of the survival horror genre.


Niche Gamer - Fingal Belmont - 10 / 10

Quote not yet available


One More Game - Vincent Ternida - 8.5 / 10

Despite its departure from the familiar urban landscapes of previous entries, Silent Hill f stands as a compelling and worthy addition to the franchise’s storied legacy. From its hauntingly atmospheric opening to its emotionally charged and unsettling finale, Hinako’s journey offers a memorable experience that will spark discussion long after the credits roll.

The game is remarkably accessible, catering to both narrative-driven players and those seeking a deeper challenge. Whether you’re here for the story or eager to test your skills with elevated puzzle and combat difficulty, Silent Hill f delivers a layered horror experience that adapts to your playstyle. While some minor issues may arise depending on personal preferences, the overall package offers something for every fan of psychological horror.


Push Square - Liam Croft - 7 / 10

Silent Hill F takes the survival horror series in a new direction, which pays off for the most part. It's quite different, and hardcore fans will have to accept that. Combat is a heavy focus, and the move to Japan means there's a different kind of tone and atmosphere in the air. Technical problems aside, it marks a bold new chapter in the Silent Hill saga. Accept it for what it is, and you'll find one of PS5's most intense experiences.


Restart.run - Len Hafer - 4 / 5

While it may not satisfy those looking for more of a classic survival horror experience, I absolutely loved the heart-wrenching and vibrantly inventive journey that was Silent Hill f. Each finished playthrough beckoned me back into the gloom to start another, even though the hairs on the back of my neck stood on end. Because I still had more questions, and Silent Hill f still had more answers. I'll be thinking about this one for a long time, and it may just become an instant horror classic.


Shacknews - Donovan Erskine - 9 / 10

Quote not yet available


SteamDeckHQ - Noah Kupetsky - 4 / 5

Silent Hill f does have flaws, but the pros heavily outweigh the cons. The story sucked me in and combat was more fun than I expected. I am being more nit-picky with the issues I’m bringing up, but they ultimately never affected my enjoyment of the game, nor made me think twice about getting back into it for round 2. And a lot of the issues I had were erased as soon as New Game+ started, which was like a weight lifted off my shoulders.

On top of that, it actually runs quite well on the Steam Deck. It’s definitely not perfect and needs compromises to run effectively, but the game is playable on the Deck and can look gorgeous. It may cost a little extra performance in 3-4 scenes, but they include graphical improvements I’d consider necessary to enjoy.

In the end, Silent Hill f is a thrilling game, and if this keeps up, the future of AAA releases from Konami is going to look very bright.


Stevivor - Matt Gosper - 9.5 / 10

Silent Hill f balances threat and reality in a way that kept me playing longer and longer per session.


The Outerhaven Productions - Karl Smart - 4.5 / 5

Silent Hill f does what the developers intended to do: Capture the soul and spirit of the first three Silent Hill games and put it into an unapologetically Japanese package. However, after playing the game, I walked away feeling like this was more like Forbidden Siren or Fatal Frame than a Silent Hill. The removal of the town itself is a big loss, but this game is one hell of a horror game that would have done really well even if it didn't have the Silent Hill brand attached to it.


TheSixthAxis - Nick Petrasiti - 10 / 10

Silent Hill f isn't just a return to form, it's a landmark entry in the series. Konami. NeoBards and Ryukishi07 have knocked it out of the park. For me, this isn't just Game of the Year material, it's an integral piece of Silent Hill history.


Wccftech - Francesco De Meo - 9 / 10

With a gripping and often disturbing story, a setting unlike anything seen before in the franchise, and gameplay that blends new ideas with a familiar framework, Silent Hill f shows that the series is not only back, but stronger than ever. While performance issues and a short runtime do impact the experience, they in no way diminish what is a triumphant return for one of the most important survival horror series ever.


Worth Playing - Chris "Atom" DeAngelus - 8.5 / 10

Silent Hill f is a slow-burn horror game that doesn't put its best foot forward, but once it has its hooks in you, they're not coming out. The compelling and well-crafted story does a fantastic job of drawing you in and keeping you invested, even potentially through multiple playthroughs. The combat mechanics can feel a tad overdone. I think Silent Hill f is the best entirely new entry in the franchise in ages, and while it has its flaws, it shows that there's still plenty of life in Konami's franchise.


XboxEra - Jesse Norris - 9 / 10

SILENT HILL f is a terrifying and terrific title. This harrowing tale of choice and consequence should thrill and properly disgust any fellow survival horror sicko.


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submitted 1 hour ago by antimidas@sopuli.xyz to c/analog@lemmy.world

Film shot at box speed, stand developed with Rodinal. This is the location of the old Crichton-Vulkan shipyard in Turku, which used to be a major shipbuilder in Finland. Some of the most significant ships to get built here were e.g. the submarines used by the Finnish navy in WWII, first of which was originally built as a prototype for the Reichsmarine. It's still possible to go see one of them, CV-707 or Vesikko, in Suomenlinna where it's on display.

The shipyard, after multiple restructurings, eventually located to Perno, Turku, and was eventually purchased by Meyer. Now it's mostly known for building the worlds largest cruise ships, such as the Royal Caribbean Icon-class. The old dry-dock and shipyard were developed into new housing, and on the right you can see some of the most expensive homes in all of Turku.

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WhenTaken (whentaken.com)

Guess when and where 5 pictures were taken.

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My sources for the preamble come mostly from here, here, and here.

The thread image depicts Kenyan police, trained by the Zionist entity, in a meeting with President Ruto before being sent to Haiti, sourced from this article.


As has been planned for the last couple years, foreign police officers have been inside Haiti for a few months now. It will surprise nobody to learn that this has not gone very well. Gangs continue to control much of the country, and violence has continued in the form of massacres and forced relocations (approximately 1.3 million). Something like 80% of the capital, Port-au-Prince, is under the control of one gang or another.

The aim by the US was to import 2500 police officers to Haiti from a wide variety of countries. One of those was Kenya; President Ruto had to fight his own country's courts to force this through, and ironically is now apparently considering withdrawing those officers once the UN mandate expires on October 2nd. The issue here is not only the limited manpower (Haiti has a population of 12 million), but also very pedestrian things, like the fact that the officers who arrive don't even speak the language.

The situation in Haiti appears to be a fairly standard operation of American national control, in which both battling sides are being supported by the US in order to create maximum disorganization and prevent a coherent political force from arising and thus threatening their Caribbean interests. While the US funds foreign forces to arrive in Haiti to "control the situation" or similar justifications, the Haitian gangs get their weapons smuggled in from the US itself. That this is happening alongside escalations against Venezuela is obviously not a coincidence - in a world in which American interests are being gradually shrugged off, and where the American state military is becoming rapidly more impotent and unable to dissuade and defeat even tiny states like Yemen, total imperial dominion of their immediate surrounding territory must be ensured by any means necessary.

The police and the gangs are likely designed to be mutually reinforcing, without even much kayfabe of fighting each other. As an example, once the Kenyan police arrived, they immediately began brutalizing anti-government protestors instead of focussing on gang activity. They were trained by the Zionist entity, after all.


Last week's thread is here.
The Imperialism Reading Group is here.

Please check out the RedAtlas!

The bulletins site is here. Currently not used.
The RSS feed is here. Also currently not used.

Israel's Genocide of Palestine

If you have evidence of Zionist crimes and atrocities that you wish to preserve, there is a thread here in which to do so.

Sources on the fighting in Palestine against the temporary Zionist entity. In general, CW for footage of battles, explosions, dead people, and so on:

UNRWA reports on Israel's destruction and siege of Gaza and the West Bank.

English-language Palestinian Marxist-Leninist twitter account. Alt here.
English-language twitter account that collates news.
Arab-language twitter account with videos and images of fighting.
English-language (with some Arab retweets) Twitter account based in Lebanon. - Telegram is @IbnRiad.
English-language Palestinian Twitter account which reports on news from the Resistance Axis. - Telegram is @EyesOnSouth.
English-language Twitter account in the same group as the previous two. - Telegram here.

English-language PalestineResist telegram channel.
More telegram channels here for those interested.

Russia-Ukraine Conflict

Examples of Ukrainian Nazis and fascists
Examples of racism/euro-centrism during the Russia-Ukraine conflict

Sources:

Defense Politics Asia's youtube channel and their map. Their youtube channel has substantially diminished in quality but the map is still useful.
Moon of Alabama, which tends to have interesting analysis. Avoid the comment section.
Understanding War and the Saker: reactionary sources that have occasional insights on the war.
Alexander Mercouris, who does daily videos on the conflict. While he is a reactionary and surrounds himself with likeminded people, his daily update videos are relatively brainworm-free and good if you don't want to follow Russian telegram channels to get news. He also co-hosts The Duran, which is more explicitly conservative, racist, sexist, transphobic, anti-communist, etc when guests are invited on, but is just about tolerable when it's just the two of them if you want a little more analysis.
Simplicius, who publishes on Substack. Like others, his political analysis should be soundly ignored, but his knowledge of weaponry and military strategy is generally quite good.
On the ground: Patrick Lancaster, an independent and very good journalist reporting in the warzone on the separatists' side.

Unedited videos of Russian/Ukrainian press conferences and speeches.

Pro-Russian Telegram Channels:

Again, CW for anti-LGBT and racist, sexist, etc speech, as well as combat footage.

https://t.me/aleksandr_skif ~ DPR's former Defense Minister and Colonel in the DPR's forces. Russian language.
https://t.me/Slavyangrad ~ A few different pro-Russian people gather frequent content for this channel (~100 posts per day), some socialist, but all socially reactionary. If you can only tolerate using one Russian telegram channel, I would recommend this one.
https://t.me/s/levigodman ~ Does daily update posts.
https://t.me/patricklancasternewstoday ~ Patrick Lancaster's telegram channel.
https://t.me/gonzowarr ~ A big Russian commentator.
https://t.me/rybar ~ One of, if not the, biggest Russian telegram channels focussing on the war out there. Actually quite balanced, maybe even pessimistic about Russia. Produces interesting and useful maps.
https://t.me/epoddubny ~ Russian language.
https://t.me/boris_rozhin ~ Russian language.
https://t.me/mod_russia_en ~ Russian Ministry of Defense. Does daily, if rather bland updates on the number of Ukrainians killed, etc. The figures appear to be approximately accurate; if you want, reduce all numbers by 25% as a 'propaganda tax', if you don't believe them. Does not cover everything, for obvious reasons, and virtually never details Russian losses.
https://t.me/UkraineHumanRightsAbuses ~ Pro-Russian, documents abuses that Ukraine commits.

Pro-Ukraine Telegram Channels:

Almost every Western media outlet.
https://discord.gg/projectowl ~ Pro-Ukrainian OSINT Discord.
https://t.me/ice_inii ~ Alleged Ukrainian account with a rather cynical take on the entire thing.


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submitted 31 minutes ago by BrikoX@lemmy.zip to c/globalnews@lemmy.zip

Unions put pressure on Prime Minister Giorgia Meloni over backing for Israel.

Archived version: https://archive.is/20250922112755/https://www.politico.eu/article/italian-workers-strike-support-gaza-palestine-state/


Disclaimer: The article linked is from a single source with a single perspective. Make sure to cross-check information against multiple sources to get a comprehensive view on the situation.

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The Death Toll (lemmygrad.ml)
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[...]

Eine Hamburger Schule gestaltete im Rahmen eines Kunstprojekts ein Magazin. Darin soll eine Schülerin abgebildet worden sein, die ein T-Shirt mit der Aufschrift „AfD Alternative für Dummheit“ trug. Die AfD wollte daraufhin in der Hamburgischen Bürgerschaft wissen, welche Kosten für das Drucken des Shirts aufgewendet worden seien, wer die Kosten getragen habe und ob das alles gegen das sogenannte Neutralitätsgebot verstoße. Der Hamburger Senat hat daraufhin tatsächlich eine Umfrage unter den Projektbeteiligten beauftragt. Die Schüler:innen, die zwei Künstlerinnen und die begleitende Kunstlehrerin mussten die Fragen der AfD beantworten.

[...]

Die AfD machte auch aus der Dienstaufsichtsbeschwerde gegen Georg Grimm, dem Lehrer aus Bayern, eine Kleine Anfrage. Grimm sagt: „Das war ein gruseliges Gefühl: zu wissen, dass eine Partei mich in einer Anfrage im Landtag namentlich nennt, Vorwürfe formuliert, aber nicht zu wissen, was genau da drin steht.“

[...]

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[Horner] had remained [since his sacking] officially employed by Red Bull as negotiations were held over the terms of his exit, with the Brit still having been owed more than £100m from a contract that had been due to run until the end of 2030.

Red Bull announced on Monday they had reached an agreement for Horner to depart, with Sky Sports F1 understanding that the 51-year-old took a reduced pay-out to ensure he will be allowed to return to the sport as soon as the summer of 2026.

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