That's true. In retrospect I also think I'm kinda comparing apples to oranges, since the drugs in those trials were also all administered intravenously so likely had a different rate of bioavailability when compared to your average prescription medication.

According to that study, activated charcoal seems to screw around with enteroenteric circulation, so I dunno if that might affect how well drugs that are taken orally are absorbed.

I might have a look further into this, see what studies I can dredge up.

[–] livestreamedcollapse@lemmy.ml 2 points 7 months ago

Yeah IV administration is definitionally 100% bioavailable; there might be some degree of the IV drug effluxing from the bloodstream, across the gut lumen, back into the intestines where orally administered charcoal could absorb it. However orally administered drugs will definitely be absorbed by oral charcoal