to be clear it's not that the British morally objected it's just that the natives were more profitable for Britain than the settlers and Britain did not want the settlers who were a bad investment comparatively to destroy the natives who were profitably exploited in the fur trade

Also the natives were a source of local armies that allowed Britain to relatively cheaply fend of Indian and Spanish claims in America if they were kept on side and very expensive to fight if they weren't. It's was no small expense to train an army in native suppression in London, equip them and then ship them thousands of miles.

source

For the settlers however the natives were simply in the way

this led to a conflict of interest in the two colonial groups

Bacon's Rebellion is such highlight of how deep this runs. Literally all lower classes, including slaves, united against the Virginia planter class, just because the Governor wouldn't genocide the Natives.

The private ownership of land is always the material cause. The lower classes of settler colonials always wants to flee their own society because of consolidated land ownership. Same as when early Virginian colonists wanted to run their own tabacco farm instead of share crop. Same as now with Israelis moving to cheaper rents in the West Bank.